Acute Effects: Short-term inhalation of benzene can cause headaches, dizziness, drowsiness, confusion and unconsciousness in humans. Short term exposure to benzene can lead to:Irritation of the respiratory tractIrritation of eyes, skin and mucous membranesDizzinessDrowsinessAbnormal heart rhythmLoss of consciousness Trichloroethylene (TCE) Fact Sheet Cecil Pearson December 16, 2016 - 9:53 am. The€EPA classifies benzene as a known human carcinogen. Health Effects Moreover, benzene may interfere with innate, humoral, and cellular immunity and disrupts the immune function contributing to its toxicity [18,19]. Risks and Health Effects/Diseases. Evaluation Of Health Effects Of Benzene Exposure to Smoking Occupational exposure to benzene is widely thought to cause leukemias that are similar to t-AML and t-MDS (44, 56, 128). 0.2.7.1 ACUTE EXPOSURE. How can benzene affect my health? Benzene in your eyes may cause general irritation and damage to your cornea. If you have been diagnosed with non-Hodgkin’s lymphoma, leukemia, or multiple myeloma and have regularly used products containing benzene, … The acute effects of over-exposure to benzene are well known in general terms. It is, however, classified as a human carcinogen and could potentially cause cancer depending on the level and extent of exposure. The chemical also can lead to anemia and a weakening of the immune system. Benzene Exposure: What Are the Long-Term Health Effects? Citation for the whole document: HEI Air Toxics Review Panel. The short term exposure limit is 5 ppm for any 15-minute period. * Exposure can cause you to feel dizzy, lightheaded, and to pass out. Humans around the world are exposed to it from multiple sources and pathways, including inhalation, through the skin, and orally. The most dangerous of benzene is the ability to cause leukemia of people who are regularly exposed to this toxic substance. Several federal agencies list the chemical as a known cause of cancer. Weakened immune system. Ethylbenzene 100-41-4 Hazard Summary Ethylbenzene is mainly used in the manufacture of styrene. Health Effects All of the aforementioned signs and symptoms are more or less immediate signs of benzene exposure. Studies show benzene exposure can increase the risk of certain cancers by as much as 40 percent. The findings: Nearly 55 percent contained benzene, a known carcinogen that can cause serious health effects with long-term exposure, according to the Centers for Disease Control and Prevention. Evidence for an association with childhood leukemia is growing. Numerous reviews over the years have described and evaluated adverse health effects associated with exposure to benzene.2 8-13 However, all of these effects were associated with occupational exposures which involve much higher benzene concentrations than are encountered in the general environment. Exposure to benzene can lead to multiple alterations that contribute to the leukemogenic process, indicating a multimodal mechanism of action. The major effect of chronic or intermittent exposure to benzene is on the blood. Benzene causes harmful effects on the bone marrow and can cause a decrease in red blood cells leading to anemia. It can also cause excessive bleeding and can affect the immune system, increasing the chance for infection. At low concentrations, the health effects benzene produces are mainly Acute Effects: Short-term inhalation of benzene can cause headaches, dizziness, drowsiness, confusion and unconsciousness in humans. In addition, From: Public Health England Published 1 … The action level is considered to be protective of public health. Important examples include the sandwich and half-sandwich complexes, respectively, Cr(C 6 H 6) 2 and [RuCl 2 (C 6 H 6)] 2. ... Benzene: 0.007 mg/day (value) California prop. Mobile-Source Air Toxics: A Critical Review of the Literature on Exposure and Health Effects. Benzene. September 2015 Benzene What is benzene? 3. Breathing benzene for a lifetime at 0.95 ppbv is very unlikely to be harmful to people. Effects on the central nervous system predominate, but benzene exposure can also cause irritation, cardiovascular effects, and effects on the kidney. Occurrence/Use. 1. However, benzene can also … (For more information on the classification systems used by these agencies, see€Known and Probable Human Carcinogens12.) (1) Health Hazard Information Acute Effects: Coexposure to benzene with ethanol (e.g., alcoholic beverages) can increase benzene toxicity in humans. Benzene Health Effects: Acute and Chronic Acute. Benzene exposure can result in a number of neurological symptoms, and these include dizziness, drowsiness, headaches, and loss of consciousness. Chronic. ... Cancerous effects. ... Other effects. ... Consumption of high levels of benzene can lead to vomiting, stomach irritation, dizziness, sleepiness, convulsion, rapid heart rate and death. Exposure to benzene can lead to multiple alterations that contribute to the leukemogenic process, indicating a multimodal mechanism of action. In addition, benzene exposure is associated with DNA damage, oxidative stress, disruption of the cell cycle, and programmed cell death leading to the development of adverse health effects [15–17]. 2007. People who smoke are exposed to approximately 10 times more benzene per year than the average non-smoker. Advances in understanding benzene health effects and susceptibility. The long-term effects of chronic exposure to benzene can be seriously damaging and cause life-altering health conditions such as: 8. Health effects. Exposure can occur occupationally, in the general environment and in the home as a result of the ubiquitous use of benzene-containing petroleum products, including motor fuels and solvents. This report is an assessment of the health effects of benzene germane to low-level exposure; it is largely a review and evaluation of the scientific literature relevant to deter- mining the human health effects of environmental exposures to benzene.
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